Recently, we proposed the Brain Symmetry Index. This index, based on spectral analysis of the EEG,  is shown to be a very sensitive feature for EEG asymmetry. Clinical applications include EEG monitoring during carotid endarterectomy and monitoring of stroke patients.

EEG  monitoring during carotid endarterectomy is in particular relevant for selective shunting. EEG monitoring with the BSI is currently a standard technique in our Hospital and in the Haga Hospital, The Hague, in carotid endarectomy. The original paper was published in 2004.

M.J.A.M. van Putten et al. A Brain Symmetry Index for online EEG monitoring in carotid endarterectomy, Clinical Neurophysiology 115 (2004) 1189-1194.

A (minor) limitation of the original BSI was the insensitivity for diffuse changes.
Recently,  therefore, I extended the BSI to capture these changes, as well:

Extended BSI for continuous EEG monitoring in carotid endarterectomy, Clinical Neurophysiology, 2006.

More details about the Brain Symmetry Index and various simulations are discussed in

The Revised Brain Symmetry Index, Clin Neurophysiology, 2007. 

The brain symmetry index was recently applied in the detection of seizure activity, as well. In particular, focal seizures induce hemispheric asymmetries. This is the rationale to evaluate  the BSI as a potential feature to detect temporal lobe seizures, as discussed in:

Michel J.A.M. van Putten, and Taco Kind and Frank Visser and Vera Lagerburg, Detecting Temporal lobe seizures from scalp EEG recordings: A comparison of various features, Clinical Neurophysiology, (2005).

This work was partially performed with the assistance of various MSc students from Delft University of Technology.

A research project with the University Medical Center Utrecht, that started in 2004, in cooperation  with the neurophysiologists Prof. C. Van Huffelen MD PhD and M. Bourre-Swart, MD, and the physicist GH Huiskamp, to study  seizure detection in asphyctic newborns, will shortly be finished. Results will be presented at the Epilepsy Congress in Paris, end August 2005.